Low Platelets and Preventing Bleeding During Cancer Treatment
Platelets are the blood cell that helps the blood to make blood clots and stop bleeding. Some cancer treatments including chemotherapy and radiation therapy can cause your platelet level or “count” to drop (thrombocytopenia). As a result, your risk of bruising and bleeding increases.
Bleeding can happen in any part of your body. Sometimes you can see the bleeding. When you have an injury, such as a cut to your skin, the bleeding is obvious. But bleeding can occur inside of your body. It may occur without injury. The bleeding may not be as obvious.
Signs and Symptoms of bleeding
Obvious signs of bleeding:
- Nose bleed
- Bright red blood in stool or urine
- Coughing up blood
- Bright red blood in vomit
- Abnormal vaginal bleeding (heavier, longer or not with your regular menses (period))
- Bleeding gums or lips or blood on your toothbrush. Blood blisters inside the mouth.
- Sudden bloodshot eyes or whites of the eyes become bloody
Less obvious signs of bleeding:
- Black tarry stool
- Severe headaches which may also come with sudden vomiting
- Visible red/purple rash-like spots on any part of your body (petechiae)
- Bruising on any part of your body
- Pain in your stomach, joints and muscles
- Shortness of breath, difficulty breathing
- Dizziness, severe headache, vision changes and/or changes in your mental status
Avoid Bleeding and Bruising
Routine appointments
- Keep all of your appointments to see your doctor and lab work checked.
- Ask when your platelet count is likely to drop.
- Come in for a platelet transfusion if your doctor feels this is needed.
- Ask if you need to stop taking any medications that may increase your risk for bleeding.
Skin Care
- Keep your skin clean and dry.
- Use a moisturizing lotion on your skin and hands regularly.
- Protect your skin from cuts, scrapes and sharp objects. Use an electric razor.
- Carefully trim and cut nails. Keep nails fairly short.
- Use lubrication during sex. You may need to avoid sex when platelets are low to prevent bleeding
Mouth Care
- Use only a soft-bristled toothbrush.
- Use dental floss only to remove plaque or debris between teeth. Do not go under the gum line with the dental floss.
- Do not use a dental pick. Do not use a toothpick.
- Use alcohol-free mouthwash.
Bowel and rectal care
- Avoid constipation.
- Use a stool softener and laxative as directed.
- Drink 6-8 cups of fluid per day.
- Get in some light exercise every day.
- Avoid straining when having a stool.
- Do NOT use suppositories or enemas.
- Do not take rectal temperatures.
Safety / Preventing Falls
- Keep your home free from clutter.
- Adjust your bead at the lowest level.
- Ask for help walking if you are weak or feel dizzy.
- Wear non-skid shoes and slippers.
- Use a night light.
- Use the stair rail when on the stairs.
- Avoid physical activity that could lead to an injury, including contact sports.
Managing Bleeding
If bleeding occurs, stay calm:
- Apply direct pressure where you are bleeding for at least 10 minutes.
- Apply an ice pack for 10-15 minutes to stop bleeding.
- Raise your arms or legs above your heart if bleeding from a limb.
- If you are bleeding from your nose:
- Gently pack the bleeding side of your nose with gauze or tissue.
- Leave the packing in place until bleeding stops.
- If you are having abnormal vaginal bleeding, note the number of pads you are using and how often you need to change.
- Note how long the bleeding is lasting.
- Prepare to call your nurse or doctor.
When To Call
- If you develop a severe headache that causes dizziness, vomiting and/or you become confused or lose consciousness - Call 911
- If you develop obvious or less obvious signs of bleeding (see the top section of this sheet).
- If you are unable to stop bleeding.
- If you have unusually heavy menstrual flow, it is lasting longer than normal.
- If you fall and hit your head.
© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.